Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140593 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2POLBHTTCHRM2 | |
| SCHEMBL2136203 | 0.80 | ALDH1A1 (0.42) | ALDH1A1POLBCHRM2CHRM1CHRM3 | |
| SCHEMBL2137357 | 0.79 | POLB (0.48) | ALDH1A1SMN1; SMN2POLBHTTCHRM2 | |
| SCHEMBL1451666 | 0.76 | POLB (0.54) | ALDH1A1SMN1; SMN2POLBHTTLMNA | |
| SCHEMBL2142156 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLBHTTCHRM2 | |
| SCHEMBL2139348 | 0.75 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2POLBHTTCHRM2 | |
| SCHEMBL2138978 | 0.75 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2POLBHTTLMNA | |
| SCHEMBL13897070 | 0.75 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2POLBHTTLMNA | |
| SCHEMBL22604709 | 0.75 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2POLBHTTLMNA | |
| SCHEMBL1196057 | 0.75 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2POLBHTTCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148484-B2 | Poly(bicyclo[2.2.1]hept-5-ene-2-carboxylic acid 2-(tert-butylamino)ethyl ester); Poly(bicyclo[2.2.1]hept-5-ene-2-carboxylic acid 2-(dimethylamino)ethyl ester); used for disinfecting, sterilizing, and preventing biofouling in closed or open industrial-water systems and cooling-water systems | KE KELIT KUNSTSTOFFWERK GESMBH (AT) | 2012-04-03 | — | — | US | disclosed |
| US-20080251460-A1 | Biocidal Polymers | KE KELIT KUNSTSTOFFWERK GESMBH (AT) | 2008-10-16 | — | — | US | disclosed |