SCHEMBL21373669

SCHEMBL21373669

CC1[CH]SCC(c2ccccc2)N1c1ccc2[nH]cnc2c1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ QPCT Q16769 17/20 0.41
▸ IP6K1 Q92551 1/20 0.36
▸ QPCTL Q9NXS2 1/20 0.34
▸ CCR5 P51681 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21373596 0.90 QPCT (0.39) QPCTQPCTL
SCHEMBL21373580 0.89 QPCT (0.41) QPCTQPCTL
SCHEMBL21373532 0.89 QPCT (0.38) QPCTQPCTL
SCHEMBL21373630 0.89 QPCT (0.41) QPCTQPCTL
SCHEMBL21373622 0.89 QPCT (0.40) QPCTIP6K1QPCTL
SCHEMBL21373675 0.86 QPCT (0.38) QPCT
SCHEMBL21373492 0.83 PIK3CD (0.32) QPCTIP6K1
SCHEMBL21373525 0.81 IP6K1 (0.33) IP6K1
SCHEMBL21373482 0.77 QPCT (0.40) QPCTIP6K1CCR5
SCHEMBL20379094 0.76 SLC6A2 (0.43) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768673-A1 COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES ETH Zurich (CH) 2021-01-27 — — EP claimed
WO-2019179890-A1 COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES ETH ZURICH (CH) 2019-09-26 — — WO claimed
EP-3543231-A1 COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES ETH Zurich (CH) 2019-09-25 — — EP claimed
EP-3568133-B1 CELL-PROTECTIVE COMPOUNDS AND THEIR USE ETH ZUERICH (CH) 2023-12-13 — — EP disclosed
CN-116462666-A Cytoprotective compounds and uses thereof 瑞士苏黎世联邦理工学院 2023-07-21 — — CN disclosed
US-11628159-B2 Cell-protective compounds and their use ETH ZURICH (CH) 2023-04-18 — — US disclosed
EP-3768673-A1 COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES ETH Zurich (CH) 2021-01-27 — — EP disclosed
US-20210015793-A1 COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES ETH ZURICH (CH) 2021-01-21 — — US disclosed
US-20190343802-A1 CELL-PROTECTIVE COMPOUNDS AND THEIR USE ETH Zürich (CH) 2019-11-14 — — US disclosed
WO-2019179890-A1 COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES ETH ZURICH (CH) 2019-09-26 — — WO disclosed
EP-3543231-A1 COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES ETH Zurich (CH) 2019-09-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190343802-A1 CELL-PROTECTIVE COMPOUNDS AND THEIR USE SRPK2, SRSF2, SRPK1 QPCT 4373/4885IP6K1 118/4885QPCTL 4255/4885
US-20210015793-A1 COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES PPT1, SPTLC1, LPCAT1 QPCT 776/4885IP6K1 1858/4885QPCTL 1175/4885
US-11628159-B2 Cell-protective compounds and their use SRPK2, SRSF2, SRPK1 QPCT 4373/4885IP6K1 118/4885QPCTL 4255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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