SCHEMBL21374404

CC(C)CC(NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)C(C)NC(=O)[C@@H]1CSSCCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)NC(Cc2ccccc2)C(=O)N1)C(=O)N[C@@H](CCC(N)=O)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	MSTN	O14793	1/20	0.54

▸	TSLP	Q969D9	3/20	0.51

▸	IL23R	Q5VWK5	3/20	0.51

▸	MDM2	Q00987	2/20	0.51

▸	KRAS	P01116	2/20	0.50

▸	F12	P00748	7/20	0.50

▸	MC4R	P32245	2/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25455504	0.73	F12 (0.59)	TSLPF12
SCHEMBL25455446	0.71	F12 (0.57)	F12
SCHEMBL25455429	0.71	F12 (0.57)	F12
SCHEMBL14948668	0.70	ESR1 (0.52)	IL23RMDM2KRAS
SCHEMBL31060626	0.69	GRPR (0.58)	IL23R
SCHEMBL1369580	0.68	KISS1R (0.66)	—
SCHEMBL24348117	0.68	SSTR2 (0.66)	—
SCHEMBL29994317	0.68	IL23R (0.52)	IL23R
SCHEMBL29359687	0.68	PTH1R (0.66)	IL23R
SCHEMBL9727453	0.68	KISS1R (0.61)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20190282654-A1	DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF	OHIO STATE INNOVATION FOUNDATION	2019-09-19	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20190282654-A1	DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF	IKBKE, IKBKB, SHARPIN	MSTN 1124/4885TSLP 2187/4885IL23R 3273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.