SCHEMBL9727453

CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	KISS1R	Q969F8	19/20	0.61

▸	NPBWR1	P48145	1/20	0.60

▸	NPFFR1	Q9GZQ6	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Tauramamide SCHEMBL29625500	0.90	NPBWR1 (0.64)	KISS1RNPBWR1NPFFR1
SCHEMBL9852839	0.88	KISS1R (0.59)	KISS1RNPBWR1NPFFR1
SCHEMBL29615834	0.86	KISS1R (0.73)	KISS1R
SCHEMBL30449287	0.86	KISS1R (0.73)	KISS1R
SCHEMBL30845372	0.86	KISS1R (0.71)	KISS1RNPBWR1NPFFR1
SCHEMBL10586420	0.85	NPY4R (0.63)	KISS1RNPBWR1
SCHEMBL9727895	0.85	PLG (0.54)	—
SCHEMBL3064845	0.85	KISS1R (0.67)	KISS1RNPBWR1NPFFR1
SCHEMBL30083992	0.85	KISS1R (0.66)	KISS1R
SCHEMBL29416090	0.85	KISS1R (0.65)	KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5140009-A	Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders	TAP PHARMACEUTICALS, INC. (US)	1992-08-18	—	—	US	disclosed
EP-0417454-A2	Reduced size LHRH analogs	ABBOTT LABORATORIES (US)	1991-03-20	—	—	EP	disclosed