SCHEMBL213752

SCHEMBL213752

Cn1cc(/C=N/O[Si](c2ccccc2)(c2ccccc2)c2ccccc2)nn1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.34
BRD4 O60885 1/20 0.33
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213753 1.00 P2RX7 (0.34) P2RX7BRD4RAB9A
SCHEMBL211448 0.81
SCHEMBL215627 0.79 BRD4 (0.39) BRD4
SCHEMBL215626 0.79 BRD4 (0.39) BRD4
SCHEMBL214179 0.74 CHRM2 (0.35) RAB9A
SCHEMBL214180 0.74 CHRM2 (0.35) RAB9A
SCHEMBL214088 0.73 HDAC1 (0.38) BRD4RAB9A
SCHEMBL214087 0.73 HDAC1 (0.38) BRD4RAB9A
SCHEMBL212302 0.73 ALDH1A1 (0.36) P2RX7RAB9A
SCHEMBL212301 0.73 ALDH1A1 (0.36) P2RX7RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed