Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179831 | 0.86 | CYP19A1 (0.32) | CYP19A1NPC1RAB9A | |
| SCHEMBL21375987 | 0.85 | — | — | |
| SCHEMBL18179706 | 0.85 | PTGDR2 (0.33) | — | |
| SCHEMBL18179614 | 0.81 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL18179619 | 0.80 | NPC1 (0.34) | CYP19A1NPC1RAB9A | |
| SCHEMBL17697064 | 0.80 | PTGS2 (0.35) | NPC1RAB9A | |
| SCHEMBL18179712 | 0.79 | PRMT6 (0.34) | — | |
| SCHEMBL22683338 | 0.76 | — | — | |
| SCHEMBL30958300 | 0.76 | — | — | |
| SCHEMBL18179548 | 0.76 | CYP19A1 (0.33) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656770-A2 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYCLES | Syngenta Participations AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3286187-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-18 | — | — | EP | disclosed |