Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376794 | 0.84 | BCL2L1 (0.52) | CES2CES1NR4A2NPC1RAB9A | |
| SCHEMBL21376318 | 0.81 | TSHR (0.45) | SRD5A2CES2CES1NPC1RAB9A | |
| SCHEMBL21376506 | 0.80 | TSHR (0.55) | SRD5A2RXRARXRBNR4A2NPC1 | |
| SCHEMBL21376784 | 0.78 | CA1 (0.61) | CES2CES1RXRANPC1RAB9A | |
| Ethane SCHEMBL10971565 | 0.77 | SRD5A2 (0.80) | SRD5A2EPHX2CYP2C8CES2CES1 | |
| SCHEMBL78879 | 0.77 | SRD5A2 (0.87) | SRD5A2EPHX2CYP2C8CES2CES1 | |
| SCHEMBL1330891 | 0.77 | SRD5A2 (0.87) | SRD5A2EPHX2CYP2C8CES2CES1 | |
| SCHEMBL23521062 | 0.75 | SRD5A2 (0.83) | SRD5A2EPHX2CYP2C8CES2CES1 | |
| SCHEMBL6762584 | 0.75 | SRD5A2 (0.83) | SRD5A2EPHX2CYP2C8CES2CES1 | |
| SCHEMBL1042428 | 0.75 | SRD5A2 (0.83) | SRD5A2EPHX2CYP2C8CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |