Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21909789 | 0.83 | HSD17B2 (0.50) | CA1CA2NPC1RAB9AKDM4E | |
| SCHEMBL21376794 | 0.83 | BCL2L1 (0.52) | NPC1POLBRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL21376318 | 0.82 | TSHR (0.45) | NPC1POLBRAB9ASMN1; SMN2CES2 | |
| SCHEMBL21376506 | 0.81 | TSHR (0.55) | NPC1POLBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL21376519 | 0.80 | NR4A2 (0.65) | NPC1POLBRAB9ASMN1; SMN2RXRA | |
| SCHEMBL17527110 | 0.79 | CA1 (0.77) | CA1CA2NPC1POLBRAB9A | |
| SCHEMBL6932815 | 0.79 | CA1 (0.77) | CA1CA2NPC1POLBRAB9A | |
| P-Anisic Acid SCHEMBL1157044 | 0.78 | CA1 (1.00) | CA1CA2NPC1POLBRAB9A | |
| P-Anisic Acid SCHEMBL43335 | 0.78 | CA1 (1.00) | CA1CA2NPC1POLBRAB9A | |
| SCHEMBL21376314 | 0.78 | SRD5A2 (0.54) | NPC1POLBRAB9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |