Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376800 | 0.89 | RAB9A (0.47) | MAPTTP53RAB9ANPC1 | |
| SCHEMBL21376793 | 0.88 | MEN1 (0.51) | MAPTTP53RAB9A | |
| SCHEMBL21376319 | 0.87 | NAMPT (0.57) | MAPTTP53RAB9A | |
| SCHEMBL21376805 | 0.87 | MEN1 (0.49) | MAPTTP53RAB9ANPC1 | |
| SCHEMBL21376915 | 0.85 | ALDH1A1 (0.62) | MAPTTP53RAB9ANPC1KCNK3 | |
| SCHEMBL21376315 | 0.84 | TP53 (0.45) | MAPTTP53RAB9A | |
| SCHEMBL7357183 | 0.82 | RAB9A (0.65) | RAB9A | |
| SCHEMBL21376320 | 0.82 | HTR2C (0.53) | MAPTTP53RAB9ANPC1 | |
| SCHEMBL21376929 | 0.80 | MAPT (0.60) | MAPTTP53RAB9ANPC1THRB | |
| SCHEMBL21909803 | 0.79 | MEN1 (0.46) | MAPTTP53RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |