⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24102167 | 0.75 | — | — | |
| SCHEMBL15149899 | 0.75 | FGF1 (0.30) | — | |
| SCHEMBL10020490 | 0.75 | FGF1 (0.30) | — | |
| SCHEMBL24098480 | 0.75 | FGF1 (0.30) | — | |
| SCHEMBL20154859 | 0.74 | — | — | |
| SCHEMBL20334696 | 0.73 | — | — | |
| SCHEMBL25492844 | 0.73 | — | — | |
| SCHEMBL25492620 | 0.71 | — | — | |
| SCHEMBL24700537 | 0.71 | LGALS8 (0.33) | — | |
| SCHEMBL21687065 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922637-A1 | MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES | Janssen Pharmaceutica NV (BE) | 2021-12-15 | — | — | EP | disclosed |
| WO-2019175260-A2 | MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE IN TAUOPATHIES | JANSSEN PHARMACEUTICA NV (BE) | 2019-09-19 | — | — | WO | disclosed |