Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898888 | 1.00 | PRMT6 (0.39) | PRMT6P2RY12ADORA1 | |
| SCHEMBL26455087 | 0.92 | P2RY12 (0.36) | PRMT6P2RY12 | |
| SCHEMBL25504694 | 0.89 | ADORA1 (0.41) | PRMT6ADORA1 | |
| SCHEMBL25505318 | 0.89 | PRMT6 (0.39) | PRMT6P2RY12ADORA1 | |
| SCHEMBL23547992 | 0.86 | PRMT6 (0.40) | PRMT6P2RY12ADORA1 | |
| SCHEMBL17589238 | 0.85 | PRMT6 (0.42) | PRMT6P2RY12ADORA1 | |
| SCHEMBL18521428 | 0.85 | ADORA1 (0.43) | PRMT6P2RY12ADORA1 | |
| SCHEMBL26435560 | 0.85 | PRMT6 (0.41) | PRMT6P2RY12ADORA1 | |
| SCHEMBL25679990 | 0.85 | PRMT6 (0.45) | PRMT6P2RY12ADORA1 | |
| SCHEMBL19146295 | 0.84 | PRMT6 (0.38) | PRMT6P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922637-A1 | MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES | Janssen Pharmaceutica NV (BE) | 2021-12-15 | — | — | EP | disclosed |
| WO-2019175260-A2 | MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE IN TAUOPATHIES | JANSSEN PHARMACEUTICA NV (BE) | 2019-09-19 | — | — | WO | disclosed |