SCHEMBL25504694

SCHEMBL25504694

CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1C[C@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)O[C@H]1CO

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 4/20 0.41
POLB P06746 1/20 0.39
KDM4E B2RXH2 1/20 0.39
PRMT6 Q96LA8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25505318 0.95 PRMT6 (0.39) ADORA1PRMT6
SCHEMBL14626242 0.91 PRMT6 (0.37) ADORA1POLBPRMT6
SCHEMBL27839 0.90 ADORA1 (0.43) ADORA1POLBKDM4EPRMT6
SCHEMBL18848392 0.90 ADORA1 (0.39) ADORA1POLBPRMT6
SCHEMBL18848394 0.90 P2RY12 (0.41) ADORA1
SCHEMBL21620263 0.90 PRMT6 (0.36) ADORA1PRMT6
SCHEMBL23898888 0.89 PRMT6 (0.39) ADORA1PRMT6
SCHEMBL21376546 0.89 PRMT6 (0.39) ADORA1PRMT6
SCHEMBL26455087 0.88 P2RY12 (0.36) PRMT6
SCHEMBL2054229 0.88 TYMP (0.39) PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159922-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2023-05-25 US disclosed