⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925373 | 0.72 | — | — | |
| SCHEMBL9788189 | 0.72 | TSHR (0.30) | — | |
| SCHEMBL12014993 | 0.68 | TSHR (0.50) | — | |
| SCHEMBL24198260 | 0.68 | — | — | |
| SCHEMBL276628 | 0.67 | — | — | |
| SCHEMBL598088 | 0.67 | — | — | |
| SCHEMBL1401388 | 0.65 | TSHR (0.35) | — | |
| SCHEMBL20609983 | 0.63 | TSHR (0.31) | — | |
| SCHEMBL998846 | 0.63 | — | — | |
| SCHEMBL21753721 | 0.63 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711304-B2 | Methods of lowering the error rate of massively parallel DNA sequencing using duplex consensus sequencing | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190284627-A1 | METHODS OF LOWERING THE ERROR RATE OF MASSIVELY PARALLEL DNA SEQUENCING USING DUPLEX CONSENSUS SEQUENCING | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION | 2019-09-19 | — | — | US | disclosed |