Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788182 | 0.76 | TSHR (0.30) | TSHR | |
| SCHEMBL600697 | 0.75 | ALDH1A1 (0.39) | TSHR | |
| SCHEMBL21376558 | 0.72 | — | — | |
| SCHEMBL9788229 | 0.72 | FDPS (0.32) | — | |
| SCHEMBL1550835 | 0.69 | — | — | |
| SCHEMBL12667673 | 0.69 | TSHR (0.33) | TSHR | |
| SCHEMBL1407498 | 0.67 | — | — | |
| SCHEMBL998846 | 0.67 | — | — | |
| SCHEMBL5169832 | 0.64 | — | — | |
| SCHEMBL14054116 | 0.63 | ALDH1A1 (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985582-A | CHEMICAL INTERMEDIATES FOR BICYCLIC RING COMPOUNDS HAVING MULTIPLE SULFUR ATOMS IN THE RING SYSTEM | THE WELLCOME FOUNDATION LTD. (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0216625-A2 | Pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-04-01 | — | — | EP | disclosed |