Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22021683 | 0.87 | NAMPT (0.32) | EPHX2CNR1NPC1NAMPT | |
| SCHEMBL22021691 | 0.86 | EPHX2 (0.50) | EPHX2CNR1ALDH1A1CES2CES1 | |
| SCHEMBL22166531 | 0.85 | EPHX2 (0.53) | EPHX2CNR1ALDH1A1CES2CES1 | |
| SCHEMBL22166535 | 0.85 | EPHX2 (0.53) | EPHX2CNR1ALDH1A1CES2CES1 | |
| SCHEMBL25567249 | 0.83 | EPHX2 (0.36) | EPHX2CNR1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL22021679 | 0.83 | EPHX2 (0.36) | EPHX2CNR1ALDH1A1NAMPTBCHE | |
| SCHEMBL14982939 | 0.83 | NAMPT (0.32) | ALDH1A1NAMPT | |
| SCHEMBL23639750 | 0.81 | NR1I2 (0.31) | EPHX2CNR1BCHEACHE | |
| SCHEMBL22021680 | 0.80 | EPHX2 (0.41) | EPHX2BCHEACHE | |
| SCHEMBL22021658 | 0.80 | EPHX2 (0.41) | EPHX2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175434-A1 | DRUG FORMULATIONS COMPRISING POLYOXAZOLINES AS MATRIX EXCIPIENT | UNIVERSITEIT GENT (BE) | 2019-09-19 | — | — | WO | disclosed |