Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21909803 | 0.88 | MEN1 (0.46) | ALDH1A1POLBKMT2AMEN1GFER | |
| SCHEMBL21376793 | 0.86 | MEN1 (0.51) | AVPR1AALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21909807 | 0.86 | HPGD (0.54) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL21376929 | 0.80 | MAPT (0.60) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL21376785 | 0.80 | MEN1 (0.54) | AVPR1AALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL21909758 | 0.79 | NPC1 (0.51) | ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL21376800 | 0.79 | RAB9A (0.47) | KMT2AMEN1MAPK1 | |
| SCHEMBL663647 | 0.78 | KMT2A (0.72) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21376321 | 0.78 | MAPT (0.52) | — | |
| SCHEMBL21376320 | 0.78 | HTR2C (0.53) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |