SCHEMBL21376776

SCHEMBL21376776

C[C@@H](c1ccccc1)N(CC(N)=O)C(=O)CN(C(=O)CN(CCCCN)C(=O)CN(C(=O)CN(C(=O)CN(CCCCN)C(=O)CN(C(=O)CN(C(=O)CN(CCCCN)C(=O)CN(C(=O)CN(C(=O)CNCCCCN)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MC3R P41968 3/20 0.65
MC4R P32245 2/20 0.65
MC1R Q01726 1/20 0.65
MC5R P33032 2/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
F2 P00734 3/20 0.34
PLG P00747 2/20 0.34
PLAT P00750 2/20 0.34
PRSS1 P07477 2/20 0.34
F10 P00742 1/20 0.34
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26256491 0.95 MC4R (0.66) MC3RMC4RMC1RMC5RF2
SCHEMBL21376777 0.95 MC4R (0.59) MC3RMC4RMC1RMC5RF2
SCHEMBL22628677 0.95 MC4R (0.59) MC3RMC4RMC1RMC5R
SCHEMBL15958510 0.95 MC3R (0.59) MC3RMC4RMC1RMC5RMAOA
SCHEMBL24603690 0.95 MC4R (0.59) MC3RMC4RMC1RMC5R
SCHEMBL24603581 0.95 MC4R (0.59) MC3RMC4RMC1RMC5R
SCHEMBL21376779 0.95 MC4R (0.59) MC3RMC4RMC1RMC5RF2
SCHEMBL22629738 0.95 MC4R (0.59) MC3RMC4RMC1RMC5R
SCHEMBL21376480 0.95 MC4R (0.59) MC3RMC4RMC1RMC5RF2
SCHEMBL21376772 0.95 MC4R (0.59) MC3RMC4RMC1RMC5RF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10815275-B2 Antimicrobial peptoids with improved selectivity and use thereof GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2020-10-27 US disclosed
US-20190284238-A1 ANTIMICROBIAL PEPTOIDS WITH IMPROVED SELECTIVITY AND USE THEREOF GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815275-B2 Antimicrobial peptoids with improved selectivity and use thereof VIP, NOD2, NGLY1 MC3R 1916/4885MC4R 1231/4885MC1R 2893/4885
US-20190284238-A1 ANTIMICROBIAL PEPTOIDS WITH IMPROVED SELECTIVITY AND USE THEREOF VIP, NOD2, FPR3 MC3R 1749/4885MC4R 1357/4885MC1R 3180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.