Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | SCD | O00767 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376338 | 0.89 | SCD (0.61) | MAPTPOLBSCDMEN1KMT2A | |
| SCHEMBL662007 | 0.83 | MAPT (1.00) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL29978725 | 0.83 | MAPT (1.00) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL21376342 | 0.82 | MAPT (0.70) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL21376333 | 0.81 | NPC1 (0.57) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL21376351 | 0.77 | LMNA (0.50) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL21376339 | 0.76 | MAPT (0.56) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL21910767 | 0.76 | SCD (0.58) | MAPTPOLBSCDMEN1KMT2A | |
| SCHEMBL21376599 | 0.74 | SCD (0.64) | MAPTPOLBSCDMEN1KMT2A | |
| SCHEMBL15478801 | 0.72 | SCD (0.62) | MAPTPOLBSCDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |