E319

E319

SCHEMBL2137723

CC(C)(C)c1cc(O)c(C(C)(C)C)cc1O.CC(C)(C)c1cc(O)ccc1O

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.91
ALOX15 P16050 5/20 0.91
LMNA P02545 3/20 0.91
HSD17B10 Q99714 2/20 0.91
TYR P14679 2/20 0.91
NR1I2 O75469 1/20 0.91
CYP2C9 P11712 1/20 0.91
MIF P14174 1/20 0.91
HTT P42858 1/20 0.91
NFE2L2 Q16236 1/20 0.91
SMN1; SMN2 Q16637 2/20 0.68
KDM4E B2RXH2 1/20 0.68
CYP1A2 P05177 1/20 0.68
MAPT P10636 1/20 0.68
ATP2A2 P16615 1/20 0.68
ATP2A3 Q93084 1/20 0.68
GAA P10253 1/20 0.57
TP53 P04637 2/20 0.50
CYP3A4 P08684 2/20 0.50
HPGD P15428 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E319 SCHEMBL29350903 0.95 ALDH1A1 (1.00) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL26745 0.95 ALDH1A1 (1.00) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL27469266 0.95 ALDH1A1 (1.00) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL10908851 0.93 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL18940889 0.93 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL18941443 0.93 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL28293722 0.93 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL10908842 0.93 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL26929486 0.93 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR
E319 SCHEMBL28120000 0.93 ALDH1A1 (0.95) ALDH1A1ALOX15LMNAHSD17B10TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110067294-A1 EFFECT OF NATURAL AND SYNTHETIC ANTIOXIDANTS ON THE OXIDATIVE STABILITY OF BIODIESEL NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2011-03-24 US claimed
WO-2009108747-A1 THE EFFECT OF NATURAL AND SYNTHETIC ANTIOXIDANTS ON THE OXIDATIVE STABILITY OF BIODIESEL WAYNE STATE UNIVERSITY (US) 2009-09-03 WO claimed
US-8657890-B2 Effect of natural and synthetic antioxidants on the oxidative stability of biodiesel WAYNE STATE UNIVERSITY (US) 2014-02-25 US disclosed
US-20110067294-A1 EFFECT OF NATURAL AND SYNTHETIC ANTIOXIDANTS ON THE OXIDATIVE STABILITY OF BIODIESEL NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2011-03-24 US disclosed
WO-2009108747-A1 THE EFFECT OF NATURAL AND SYNTHETIC ANTIOXIDANTS ON THE OXIDATIVE STABILITY OF BIODIESEL WAYNE STATE UNIVERSITY (US) 2009-09-03 WO disclosed