SCHEMBL2137947

SCHEMBL2137947

CCO[Si](CCCSSCCC[Si](OCC)(OCC)OCCCN(C)C)(OCC)OCCCN(C)C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2139492 0.94 KDM4E (0.33) KDM4EALDH1A1SMN1; SMN2
SCHEMBL2139996 0.92
SCHEMBL5130298 0.85 SLC2A1 (0.39)
SCHEMBL2140149 0.85
SCHEMBL51414 0.82
SCHEMBL2141291 0.80 SLC2A1 (0.37)
SCHEMBL329406 0.80 ALDH1A1 (0.39) KDM4EALDH1A1SMN1; SMN2
SCHEMBL3853819 0.80
SCHEMBL2140583 0.80 SLC2A1 (0.37) KDM4EALDH1A1
SCHEMBL15612040 0.79 ALDH1A1 (0.39) KDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2246355-B1 ORGANIC SILICON COMPOUND, AND RUBBER COMPOSITIONS, TIRES, PRIMER COMPOSITIONS, PAINT COMPOSITIONS, AND ADHESIVES USING SAME BRIDGESTONE CORP (JP) 2015-12-23 EP disclosed
US-8183403-B2 Organosilicon compound as well as rubber composition, tire, primer composition, paint composition and adhesive using the same BRIDGESTONE CORPORATION (JP) 2012-05-22 US disclosed
US-20110054095-A1 ORGANOSILICON COMPOUND AS WELL AS RUBBER COMPOSITION, TIRE, PRIMER COMPOSITION, PAINT COMPOSITION AND ADHESIVE USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054095-A1 ORGANOSILICON COMPOUND AS WELL AS RUBBER COMPOSITION, TIRE, PRIMER COMPOSITION, PAINT COMPOSITION AND ADHESIVE USING THE SAME SRRT, ILK, TERB1 KDM4E 1708/4885ALDH1A1 2235/4885SMN1; SMN2 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.