SCHEMBL2138068

SCHEMBL2138068

CC(O)Cc1ccccc1/C=C/C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 12/20 0.55
PTGER2 P43116 11/20 0.55
PTGER4 P35408 9/20 0.55
PTGDR Q13258 5/20 0.52
TBXA2R P21731 4/20 0.52
PTGER1 P34995 4/20 0.50
PTGFR P43088 3/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
NFKB1 P19838 1/20 0.50
CA4 P22748 1/20 0.50
PTGIR P43119 2/20 0.49
TBXAS1 P24557 1/20 0.47
KDM4E B2RXH2 1/20 0.46
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
HDAC3 O15379 1/20 0.43
TNKS O95271 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1716473 0.89 PTGER3 (0.56) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL10410675 0.86 PTGER3 (0.54) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL10409217 0.84 PTGER3 (0.52) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL29045408 0.83 PTGER3 (0.52) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL28747085 0.82 PTGER3 (0.56) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL28747086 0.82 PTGER3 (0.56) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL309761 0.81 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL1150939 0.81 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL3214322 0.81 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL3557041 0.80 PTGER3 (0.61) PTGER3PTGER2PTGER4PTGDRTBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110006245-A1 POLYMER COATED INORGANIC FINE PARTICLE AND METHOD FOR PREPARING THE SAME TAMAGAWA SEIKI CO., LTD. (JP) 2011-01-13 US disclosed
EP-2221327-A1 POLYMER-COATED FINE INORGANIC PARTICLE AND PROCESS FOR PRODUCING THE SAME Handa, Hiroshi (JP) 2010-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110006245-A1 POLYMER COATED INORGANIC FINE PARTICLE AND METHOD FOR PREPARING THE SAME CYP4F12, CYP2F1, CYP4F3 PTGER3 2483/4885PTGER2 1382/4885PTGER4 2638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.