SCHEMBL29045408

SCHEMBL29045408

COC(C)Cc1ccccc1/C=C/C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 14/20 0.52
PTGER2 P43116 13/20 0.52
PTGER4 P35408 11/20 0.52
PTGDR Q13258 5/20 0.49
TBXA2R P21731 4/20 0.49
KDM4E B2RXH2 1/20 0.49
PTGER1 P34995 5/20 0.47
PTGFR P43088 3/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
NFKB1 P19838 1/20 0.46
CA4 P22748 1/20 0.46
PTGIR P43119 2/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.44
TBXAS1 P24557 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1716473 0.84 PTGER3 (0.56) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL2138068 0.83 PTGER3 (0.55) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL10410675 0.82 PTGER3 (0.54) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL10409217 0.81 PTGER3 (0.52) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL8573281 0.78 PTGER3 (0.57) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL28747085 0.78 PTGER3 (0.56) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL28747086 0.78 PTGER3 (0.56) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL3214322 0.77 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL309761 0.77 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL1150939 0.77 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514679-A Palladium-catalyzed sp with low-cost and high-efficiency quaternary ammonium nitrate as oxidant 2 And sp (sp) 3 Carbon hydrogen bond alkenylation method 南京工业大学 2023-08-01 CN disclosed