Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139867 | 0.97 | CA12 (0.35) | METKDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL2137177 | 0.95 | MET (0.37) | METAKR1B10AKR1B1KDM4EMAPT | |
| SCHEMBL679370 | 0.95 | MET (0.37) | METAKR1B10AKR1B1KDM4EMAPT | |
| SCHEMBL28658369 | 0.90 | MAPT (0.38) | METAKR1B10AKR1B1KDM4EMAPT | |
| SCHEMBL2140734 | 0.90 | MAPT (0.38) | METAKR1B10AKR1B1KDM4EMAPT | |
| SCHEMBL2140070 | 0.89 | MET (0.38) | METAKR1B10AKR1B1KDM4EMAPT | |
| SCHEMBL1564285 | 0.88 | MET (0.39) | METAKR1B10AKR1B1KDM4EMAPT | |
| SCHEMBL3633052 | 0.88 | MET (0.39) | METAKR1B10AKR1B1KDM4EMAPT | |
| SCHEMBL1565147 | 0.87 | MET (0.39) | METAKR1B10AKR1B1KDM4EMAPT | |
| SCHEMBL2137166 | 0.87 | AKR1B10 (0.41) | METAKR1B10AKR1B1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | ROLIC AG (CH) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | PARG, PARN, PUF60 | MET 4377/4885AKR1B10 2792/4885AKR1B1 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.