Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342468 | 1.00 | CES2 (0.48) | CES2CES1CYP3A4GABRA1GABRB2 | |
| SCHEMBL14088059 | 1.00 | CES2 (0.48) | CES2CES1CYP3A4GABRA1GABRB2 | |
| SCHEMBL625219 | 1.00 | CES2 (0.48) | CES2CES1CYP3A4GABRA1GABRB2 | |
| SCHEMBL29609066 | 1.00 | CES2 (0.48) | CES2CES1CYP3A4GABRA1GABRB2 | |
| Phthalic Acid SCHEMBL3628213 | 0.84 | CES2 (0.54) | CES2CES1CYP3A4MEN1KMT2A | |
| Phthalic Acid SCHEMBL3628215 | 0.84 | CES2 (0.54) | CES2CES1CYP3A4MEN1KMT2A | |
| SCHEMBL9667214 | 0.83 | PDE2A (0.50) | CES2CES1CYP3A4GABRA1GABRB2 | |
| SCHEMBL11602791 | 0.81 | CES2 (0.54) | CES2CES1CYP3A4ACHEIDO1 | |
| SCHEMBL23363630 | 0.81 | CES2 (0.52) | CES2CES1CYP3A4GABRA1GABRB2 | |
| SCHEMBL5684729 | 0.81 | CES2 (0.46) | CES2CES1CYP3A4GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110002961-B | Method for racemization-free synthesis of chiral alcohol | 三峡大学 | 2022-05-03 | — | — | CN | claimed |
| CN-105087671-A | Method for preparing (S)-fluoro-phenyl ethanol with penicillium | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-11-25 | — | — | CN | claimed |
| EP-1505155-B1 | CARBONYL REDUCTASE, GENE THEREOF AND USE OF THE SAME | KANEKA CORP (JP) | 2008-12-03 | — | — | EP | claimed |
| US-7332312-B2 | Polynucleotide encoding a polypeptide having activity in asymmetrically reducing 2-chloro-1-(3'-chlorophenyl)ethanone, for producing optically active 3-hydroxy ester derivatives | KANEKA CORPORATION (JP) | 2008-02-19 | — | — | US | claimed |
| US-20060046289-A1 | Novel carbonyl reductase, gene thereof and use of the same | KANEKA CORPORATION (JP) | 2006-03-02 | — | — | US | claimed |
| EP-1505155-A1 | NOVEL CARBONYL REDUCTASE, GENE THEREOF AND USE OF THE SAME | KANEKA CORPORATION (JP) | 2005-02-09 | — | — | EP | claimed |
| US-12281058-B2 | Manganese catalysts and their use in hydrogenation of ketones | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2025-04-22 | — | — | US | disclosed |
| CN-112716927-B | Alpha-amino amide compound and preparation method and application thereof | 复旦大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-110002961-B | Method for racemization-free synthesis of chiral alcohol | 三峡大学 | 2022-05-03 | — | — | CN | disclosed |
| US-20220119329-A1 | Manganese Catalysts and Their Use in Hydrogenation of Ketones | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2022-04-21 | — | — | US | disclosed |
| US-11174268-B2 | Benzenesulfonamide compouds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2021-11-16 | — | — | US | disclosed |
| US-11174268-B2 | Benzenesulfonamide compouds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2021-11-16 | — | — | US | disclosed |
| US-7332312-B2 | Polynucleotide encoding a polypeptide having activity in asymmetrically reducing 2-chloro-1-(3'-chlorophenyl)ethanone, for producing optically active 3-hydroxy ester derivatives | KANEKA CORPORATION (JP) | 2008-02-19 | — | — | US | disclosed |
| US-7332312-B2 | Polynucleotide encoding a polypeptide having activity in asymmetrically reducing 2-chloro-1-(3'-chlorophenyl)ethanone, for producing optically active 3-hydroxy ester derivatives | KANEKA CORPORATION (JP) | 2008-02-19 | — | — | US | disclosed |
| US-7332312-B2 | Polynucleotide encoding a polypeptide having activity in asymmetrically reducing 2-chloro-1-(3'-chlorophenyl)ethanone, for producing optically active 3-hydroxy ester derivatives | KANEKA CORPORATION (JP) | 2008-02-19 | — | — | US | disclosed |
| CN-101016526-A | Oxidization microbacterium and method of preparing optical pure chiral aryl secondary alcohol by the same | UNIV EAST CHINA SCIENCE & TECH (CN) | 2007-08-15 | — | — | CN | disclosed |
| US-20060046289-A1 | Novel carbonyl reductase, gene thereof and use of the same | KANEKA CORPORATION (JP) | 2006-03-02 | — | — | US | disclosed |
| EP-1505155-A1 | NOVEL CARBONYL REDUCTASE, GENE THEREOF AND USE OF THE SAME | KANEKA CORPORATION (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-5296484-A | Applying fungicide to locus of plant pathogen | DOWELANCO (US) | 1994-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281058-B2 | Manganese catalysts and their use in hydrogenation of ketones | CYC1, SCO2, MT-CO3 | CES2 2134/4885CES1 2530/4885CYP3A4 1922/4885 |
| US-11174268-B2 | Benzenesulfonamide compouds and their use as therapeutic agents | KCND2, SCN1A, CACNA1D | CES2 446/4885CES1 778/4885CYP3A4 414/4885 |
| US-20060046289-A1 | Novel carbonyl reductase, gene thereof and use of the same | CBR3, CBR1, ADH1C | CES2 1212/4885CES1 799/4885CYP3A4 686/4885 |
| US-20220119329-A1 | Manganese Catalysts and Their Use in Hydrogenation of Ketones | CYC1, SCO2, MT-CO3 | CES2 2134/4885CES1 2530/4885CYP3A4 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.