SCHEMBL21383076

SCHEMBL21383076

I[SiH](c1ccccc1)c1ccccc1.[H+]

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TSHR P16473 4/20 0.32
DAO P14920 1/20 0.32
NAPRT Q6XQN6 1/20 0.32
ALOX12 P18054 2/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
CASP1 P29466 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
CA12 O43570 1/20 0.30
GLA P06280 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA14 Q9ULX7 1/20 0.30
LMNA P02545 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23321588 0.97 ALDH1A1 (0.35) ALDH1A1TSHRDAONAPRTALOX12
Benzene SCHEMBL28149844 0.76 ALDH1A1 (0.35) ALDH1A1TSHRDAONAPRTALOX12
SCHEMBL8373369 0.76
SCHEMBL8372403 0.71
SCHEMBL21527935 0.71
SCHEMBL24624087 0.71
SCHEMBL1777339 0.71
SCHEMBL3482296 0.67 ALDH1A1 (0.40) ALDH1A1TSHRDAONAPRTALOX12
SCHEMBL38902 0.67 ALDH1A1 (0.40) ALDH1A1TSHRDAONAPRTALOX12
Benzene SCHEMBL27873242 0.67 ALDH1A1 (0.40) ALDH1A1TSHRDAONAPRTALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768733-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP claimed
US-20210017311-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2021-01-21 US claimed
WO-2019182993-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO claimed
US-12037462-B2 Polyolefin-polydiorganosiloxane block copolymer and method for the synthesis thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-16 US disclosed
US-11814555-B2 Hot melt adhesive compositions containing polyolefin-polydiorganosiloxane copolymers and methods for the preparation and use thereof DOW SILICONES CORPORATION (US) 2023-11-14 US disclosed
EP-3768793-B1 POLYORGANOSILOXANE HOT MELT ADHESIVE COMPOSITIONS CONTAINING POLYOLEFIN - POLYDIORGANOOSILOXANE COPOLYMERS AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORP (US) 2023-09-27 EP disclosed
EP-3768792-B1 HOT MELT ADHESIVE COMPOSITION CONTAINING A POLYOLEFIN - POLYDIORGANOSILOXANE COPOLYMER AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORP (US) 2023-09-20 EP disclosed
US-11702512-B2 Polysiloxane resin-polyolefin copolymer and methods for the preparation and use thereof DOW SILICONES CORPORATION (US) 2023-07-18 US disclosed
EP-3768765-B1 POLYOLEFIN-POLYDIORGANOSILOXANE BLOCK COPOLYMER AND HYDROSILYLATON REACTION METHOD FOR THE SYNTHESIS THEREOF DOW SILICONES CORP (US) 2023-05-17 EP disclosed
US-11332583-B2 Polyolefin-polydiorganosiloxane block copolymer and hydrosilylation reaction method for the synthesis thereof DOW SILICONES CORPORATION (US) 2022-05-17 US disclosed
US-11193051-B2 Hot melt adhesive composition containing a polyolefin-polydiorganosiloxane copolymer and methods for the preparation and use thereof DOW SILICONES CORPORATION (US) 2021-12-07 US disclosed
US-20200407512-A1 POLYOLEFIN-POLYDIORGANOSILOXANE BLOCK COPOLYMER AND METHOD FOR THE SYNTHESIS THEREOF DOW SILICONES CORP (US) 2020-12-31 US disclosed
US-20200407600-A1 HOT MELT ADHESIVE COMPOSITIONS CONTAINING POLYOLEFIN-POLYDIORGANOSILOXANE COPOLYMERS AND METHODS FOR THE PREPARATION AND USE THEREOF DOW GLOBAL TECHNOLOGIES LLC 2020-12-31 US disclosed
WO-2020018159-A1 POLYSILOXANE RESIN - POLYOLEFIN COPOLYMER AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORPORATION (US) 2020-01-23 WO disclosed
WO-2019182718-A1 HOT MELT ADHESIVE COMPOSITION CONTAINING A POLYOLEFIN - POLYDIORGANOSILOXANE COPOLYMER AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORPORATION (US) 2019-09-26 WO disclosed
WO-2019182720-A1 POLYOLEFIN-POLYDIORGANOSIIOXANE BLOCK COPOLYMER AND METHOD FOR THE SYNTHESIS THEREOF DOW SILICONES CORPORATION (US) 2019-09-26 WO disclosed
WO-2019182993-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
WO-2019182721-A1 POLYOLEFIN-POLYDIORGANOSILOXANE BLOCK COPOLYMER AND HYDROSILYLATON REACTION METHOD FOR THE SYNTHESIS THEREOF DOW SILICONES CORPORATION (US) 2019-09-26 WO disclosed
WO-2019182992-A1 PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
WO-2019182719-A1 POLYORGANOSILOXANE HOT MELT ADHESIVE COMPOSITIONS CONTAINING POLYOLEFIN - POLYDIORGANOOSILOXANE COPOLYMERS AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORPORATION (US) 2019-09-26 WO disclosed