Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17912674 | 0.88 | NR4A2 (0.54) | NR3C1PGRNR3C2ARHDAC3 | |
| SCHEMBL21383594 | 0.85 | HDAC3 (0.50) | NR3C1PGRNR3C2ARHDAC3 | |
| SCHEMBL28885915 | 0.85 | NR4A2 (0.50) | NR3C1PGRNR3C2ARMEN1 | |
| SCHEMBL21383578 | 0.83 | NR4A2 (0.58) | GUSBNR4A2MGAMGAASI | |
| SCHEMBL21399536 | 0.83 | NR4A2 (0.58) | TDP1GUSBNR4A2MGAMGAA | |
| SCHEMBL21399703 | 0.83 | HDAC3 (0.59) | NR3C1PGRNR3C2ARHDAC3 | |
| SCHEMBL21399535 | 0.82 | NR4A2 (0.59) | GUSBNR4A2MGAMGAASI | |
| SCHEMBL7298601 | 0.82 | GUSB (0.48) | GUSBMGAMGAASIMGAM2 | |
| SCHEMBL21399537 | 0.82 | MAP2K4 (0.52) | MEN1MAPTKMT2AGUSBRAB9A | |
| SCHEMBL28501875 | 0.82 | RAB9A (0.47) | NR3C1PGRNR3C2ARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024499-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | XIAMEN UNIVERSITY (CN) | 2021-01-28 | — | — | US | disclosed |
| WO-2019183527-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019183527-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024499-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | BCL2, BCOR, BCLAF1 | NR3C1 71/4885PGR 893/4885NR3C2 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.