Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | SI | P14410 | 4/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510174 | 0.86 | NR4A2 (0.50) | NR4A2MGAMGAASIMGAM2 | |
| SCHEMBL21383576 | 0.82 | NR3C1 (0.58) | RAB9ANR4A2CREBBPGPR84KMT2A | |
| SCHEMBL17912674 | 0.81 | NR4A2 (0.54) | RAB9ANR4A2CREBBPGPR84KMT2A | |
| SCHEMBL28516235 | 0.80 | GUSB (0.45) | GPR84KMT2AL3MBTL1MEN1MAPT | |
| SCHEMBL21383594 | 0.78 | HDAC3 (0.50) | KMT2AL3MBTL1MGAMGAASI | |
| SCHEMBL28885915 | 0.78 | NR4A2 (0.50) | RAB9ANR4A2CREBBPGPR84KMT2A | |
| SCHEMBL4059622 | 0.75 | KDM4E (0.53) | KMT2AL3MBTL1GAAMEN1MAPT | |
| SCHEMBL6215224 | 0.72 | POLB (0.41) | RAB9AKMT2AL3MBTL1GAAMEN1 | |
| SCHEMBL28507976 | 0.72 | GUSB (0.47) | KMT2AMGAMGAASIMGAM2 | |
| SCHEMBL6797310 | 0.72 | ADORA2A (0.47) | KMT2AMEN1MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218852-A | Oxidized bis (3-indolyl) methane and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2021-01-12 | — | — | CN | claimed |
| CN-112218852-A | Oxidized bis (3-indolyl) methane and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2021-01-12 | — | — | CN | disclosed |