SCHEMBL21384271

SCHEMBL21384271

CC1=C(C)C(=O)N(CCN)C1=O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
PKM P14618 1/20 0.52
HEXA P06865 3/20 0.44
HEXB P07686 3/20 0.44
MAPK1 P28482 3/20 0.33
MAOA P21397 3/20 0.33
MAOB P27338 3/20 0.33
LCK P06239 2/20 0.33
CISD1 Q9NZ45 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22403740 0.85 ALDH1A1 (0.48) ALDH1A1PKMHEXAHEXBLCK
SCHEMBL10901592 0.83 ALDH1A1 (0.61) ALDH1A1PKM
SCHEMBL22403741 0.83 ALDH1A1 (0.38) ALDH1A1PKMHEXAHEXBMAPK1
SCHEMBL22403737 0.78 ALDH1A1 (0.44) ALDH1A1PKM
SCHEMBL15975535 0.78 ALDH1A1 (0.56) ALDH1A1PKMMAPK1
SCHEMBL14377618 0.78 ALDH1A1 (0.56) ALDH1A1PKMMAPK1MAOB
SCHEMBL240018 0.76 ALDH1A1 (0.54) ALDH1A1PKMMAPK1MAOB
SCHEMBL15975537 0.76 ALDH1A1 (0.54) ALDH1A1PKMMAPK1MAOB
SCHEMBL9563132 0.76 ALDH1A1 (0.54) ALDH1A1PKMMAPK1CISD1
SCHEMBL10703043 0.76 ALDH1A1 (0.54) ALDH1A1PKMMAPK1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PROMERUS, LLC (US) 2024-10-10 US claimed
US-20240288770-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITIONS PROMERUS, LLC (US) 2024-08-29 US claimed
US-11535709-B2 Reactive end group containing polyimides and polyamic acids and photosensitive compositions thereof PROMERUS, LLC (US) 2022-12-27 US claimed
US-20200283579-A1 REACTIVE END GROUP CONTAINING POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2020-09-10 US claimed
US-20200285151-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITIONS PROMERUS, LLC (US) 2020-09-10 US claimed
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PROMERUS, LLC (US) 2024-10-10 US disclosed
US-20240288770-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITIONS PROMERUS, LLC (US) 2024-08-29 US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
US-11535709-B2 Reactive end group containing polyimides and polyamic acids and photosensitive compositions thereof PROMERUS, LLC (US) 2022-12-27 US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 US disclosed
EP-3768294-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS Carmot Therapeutics, Inc. (US) 2021-01-27 EP disclosed
CN-112236161-A Modulators of G protein-coupled receptors 卡莫特治疗学股份有限公司 2021-01-15 CN disclosed
US-20200285151-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITIONS PROMERUS, LLC (US) 2020-09-10 US disclosed
US-20200285151-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITIONS PROMERUS, LLC (US) 2020-09-10 US disclosed
US-20200283579-A1 REACTIVE END GROUP CONTAINING POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2020-09-10 US disclosed
US-20200283579-A1 REACTIVE END GROUP CONTAINING POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2020-09-10 US disclosed
WO-2019183577-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. (US) 2019-09-26 WO disclosed
WO-2019183577-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. (US) 2019-09-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR ALDH1A1 3305/4885PKM 2323/4885HEXA 2205/4885
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PUF60, FTO, PARN ALDH1A1 2713/4885PKM 98/4885HEXA 4062/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR ALDH1A1 3367/4885PKM 2277/4885HEXA 2427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.