Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26634652 | 1.00 | GAA (0.36) | GAAACEUSP2AKT1HTR1A | |
| SCHEMBL26634656 | 1.00 | GAA (0.36) | GAAACEUSP2AKT1HTR1A | |
| SCHEMBL21389372 | 0.79 | L3MBTL1 (0.38) | GAAUSP2ALDH1A1FABP3FABP4 | |
| SCHEMBL21383940 | 0.79 | L3MBTL1 (0.38) | GAAUSP2ALDH1A1FABP3FABP4 | |
| SCHEMBL24796626 | 0.79 | L3MBTL1 (0.38) | GAAUSP2ALDH1A1FABP3FABP4 | |
| SCHEMBL24795884 | 0.79 | USP2 (0.37) | GAAUSP2ALDH1A1FABP3FABP4 | |
| SCHEMBL21389230 | 0.79 | USP2 (0.37) | GAAUSP2ALDH1A1FABP3FABP4 | |
| SCHEMBL21389301 | 0.78 | FABP3 (0.34) | GAAUSP2ALDH1A1FABP3FABP4 | |
| SCHEMBL21383821 | 0.78 | FABP3 (0.34) | GAAUSP2ALDH1A1FABP3FABP4 | |
| SCHEMBL26634663 | 0.78 | FABP3 (0.34) | GAAUSP2ALDH1A1FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768294-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | Carmot Therapeutics, Inc. (US) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |