Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384612 | 1.00 | L3MBTL1 (0.43) | L3MBTL1LMNACNR1EPHX2CACNA1G | |
| SCHEMBL21396932 | 0.83 | F10 (0.39) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21385835 | 0.76 | MEN1 (0.42) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21385836 | 0.76 | MEN1 (0.42) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30574421 | 0.75 | MEN1 (0.41) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30574424 | 0.75 | MEN1 (0.41) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28456220 | 0.72 | MAPT (0.48) | L3MBTL1LMNAMAPTMEN1KMT2A | |
| SCHEMBL21182270 | 0.68 | IDO1 (0.50) | L3MBTL1LMNACNR1MAPTSMN1; SMN2 | |
| SCHEMBL21187088 | 0.68 | IDO1 (0.50) | L3MBTL1LMNACNR1MAPTSMN1; SMN2 | |
| SCHEMBL21182269 | 0.68 | IDO1 (0.50) | L3MBTL1LMNACNR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |