Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384612 | 0.83 | L3MBTL1 (0.43) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL21384615 | 0.83 | L3MBTL1 (0.43) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL21385836 | 0.80 | MEN1 (0.42) | F10MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL21385835 | 0.80 | MEN1 (0.42) | F10MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30574424 | 0.74 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL30574421 | 0.74 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL30574427 | 0.72 | CHRNB2 (0.42) | F10CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL21385166 | 0.72 | CHRNB2 (0.42) | F10CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28456220 | 0.71 | MAPT (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL21384592 | 0.68 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |