Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532598 | 0.82 | MEN1 (0.59) | RXFP1CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL24823440 | 0.80 | TOP1 (0.53) | CYP1A2CYP2D6CYP2C19CYP3A4MAPT | |
| SCHEMBL23336404 | 0.79 | P2RX1 (0.76) | RXFP1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4432968 | 0.78 | POLB (0.54) | RXFP1CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL5429717 | 0.78 | POLB (0.54) | RXFP1CYP1A2CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL28860522 | 0.78 | ALDH1A1 (0.48) | RXFP1CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL30100391 | 0.77 | TMPRSS4 (0.79) | CYP1A2CYP2D6CYP2C19CYP3A4MAPT | |
| SCHEMBL18341401 | 0.77 | TMPRSS4 (0.79) | CYP1A2CYP2D6CYP2C19CYP3A4MAPT | |
| SCHEMBL15531106 | 0.77 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL21394911 | 0.76 | TMPRSS4 (0.58) | RXFP1CYP1A2CYP2D6CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |