SCHEMBL21385276

SCHEMBL21385276

Brc1cccc(-c2cccc(-c3ccc4cccc5c4c3-c3cccnc3S5)c2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BIRC5 O15392 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTT P42858 1/20 0.34
GRM5 P41594 1/20 0.32
TYMS P04818 1/20 0.32
CYP19A1 P11511 1/20 0.32
POLB P06746 1/20 0.32
ALDH1A1 P00352 3/20 0.31
ALOX15 P16050 1/20 0.31
MAPK10 P53779 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HPGD P15428 2/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
MAPT P10636 1/20 0.31
HK1 P19367 1/20 0.31
RAB9A P51151 1/20 0.31
HKDC1 Q2TB90 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21383215 0.96 BIRC5 (0.34) BIRC5CYP1A2CYP2C19HTTGRM5
SCHEMBL21385289 0.86 TYMS (0.35) CYP1A2CYP2C19HTTTYMSPOLB
SCHEMBL21385095 0.81 IDO1 (0.34) BIRC5HTTGRM5ALDH1A1ALOX15
SCHEMBL21382842 0.81 LPL (0.36)
SCHEMBL21385107 0.79 TYMS (0.39) CYP1A2CYP2C19HTTTYMSPOLB
SCHEMBL21382886 0.77 LIPG (0.39)
SCHEMBL21382718 0.71 TYMS (0.42) BIRC5CYP1A2TYMSPOLBALDH1A1
SCHEMBL16629647 0.71 KDM4E (0.48) BIRC5CYP1A2CYP2C19HTTGRM5
SCHEMBL22204606 0.70 TSHR (0.44) BIRC5HTTALDH1A1ALOX15HSD17B10
SCHEMBL21385090 0.70 TYMS (0.44) BIRC5CYP1A2TYMSPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019182360-A1 COMPOUND, ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY DEVICE 에스케이머티리얼즈 주식회사 2019-09-26 WO disclosed