Biphenyl

Biphenyl

SCHEMBL21385286

O=[PH](O)On1c(=S)oc2ccccc21.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.45
ALDH1A1 P00352 8/20 0.45
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 2/20 0.41
HTT P42858 6/20 0.39
MAPT P10636 5/20 0.39
LMNA P02545 5/20 0.39
RAB9A P51151 3/20 0.39
NPC1 O15118 3/20 0.39
MDM2 Q00987 2/20 0.39
PAX8 Q06710 1/20 0.39
MITF O75030 1/20 0.34
MEN1 O00255 6/20 0.33
IDO1 P14902 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
GAA P10253 2/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4370888 0.94 ALDH1A1 (0.46) KMT2AALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL4370885 0.82 ALDH1A1 (0.44) KMT2AALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL2432650 0.76 MAOB (0.32) KMT2AALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL8550634 0.70 ALDH1A1 (0.49) KMT2AALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL8550636 0.69 ALDH1A1 (0.44) KMT2AALDH1A1SMN1; SMN2HPGDHTT
Biphenyl SCHEMBL9009481 0.62 ALDH1A1 (0.47) KMT2AALDH1A1SMN1; SMN2HTTMAPT
SCHEMBL14553911 0.62 ALDH1A1 (1.00) KMT2AALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL11192533 0.62 MAPT (0.53) KMT2AALDH1A1SMN1; SMN2HPGDHTT
Biphenyl SCHEMBL11137586 0.61 ALDH1A1 (0.60) KMT2AALDH1A1SMN1; SMN2HTTMAPT
Biphenyl SCHEMBL987489 0.61 ALDH1A1 (0.60) KMT2AALDH1A1SMN1; SMN2HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019189416-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2019-10-03 WO disclosed
WO-2019181878-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2019-09-26 WO disclosed
WO-2019181879-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNED FILM AND LIQUID CRYSTAL DISPLAY DEVICE 日産化学株式会社 2019-09-26 WO disclosed