Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196544 | 0.85 | HPGD (0.69) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL6893802 | 0.84 | MAPT (0.65) | MAPTALDH1A1APEX1KMT2AMEN1 | |
| SCHEMBL2947194 | 0.81 | HPGD (0.73) | ALDH1A1HTTHPGDNPSR1MAPK1 | |
| SCHEMBL17156221 | 0.76 | MIF (0.68) | MAPTALDH1A1POLBHPGDMAPK1 | |
| SCHEMBL1101916 | 0.75 | ALDH1A1 (0.54) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11074949 | 0.75 | MAPT (0.51) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11556953 | 0.72 | ALDH1A1 (0.62) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL14246927 | 0.72 | ALDH1A1 (0.58) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL7814099 | 0.72 | PTPN1 (0.52) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL9873167 | 0.71 | MAPT (0.45) | MAPTALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4422865-A | HERBICIDES AND PLANT GROWTH REGULANTS | MONSANTO COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4362547-A | HERBICIDES; PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1982-12-07 | — | — | US | disclosed |
| US-4289886-A | HERBICIDES, PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1981-09-15 | — | — | US | disclosed |