Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23126916 | 0.79 | KDM1A (0.35) | KDM1ANPY5R | |
| SCHEMBL668941 | 0.79 | CA1 (0.50) | KDM1A | |
| SCHEMBL18236676 | 0.78 | SAT1 (0.35) | KDM1A | |
| SCHEMBL18236985 | 0.77 | NR1D1 (0.32) | KDM1A | |
| SCHEMBL16442244 | 0.77 | CA1 (0.38) | KDM1A | |
| SCHEMBL14365952 | 0.77 | KMT2A (0.37) | — | |
| SCHEMBL6050956 | 0.76 | CA1 (0.54) | — | |
| SCHEMBL13194108 | 0.74 | KDM1A (0.33) | KDM1ANPY5R | |
| SCHEMBL10321356 | 0.74 | ALDH1A1 (0.35) | KDM1ANPY5R | |
| SCHEMBL67104 | 0.74 | CYP3A4 (0.35) | KDM1ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127499-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CALICO LIFE SCIENCES LLC (US) | 2021-06-24 | — | — | WO | disclosed |
| EP-3294732-B1 | BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | GILEAD SCIENCES INC (US) | 2019-09-25 | — | — | EP | disclosed |