Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.51 |
| ▸ | RELA | Q04206 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445838 | 0.88 | KDM4E (0.60) | KDM4ETNFNOD1RAB9ANFKB1 | |
| SCHEMBL20349432 | 0.88 | KDM4E (0.60) | KDM4ETNFNOD1RAB9ANFKB1 | |
| SCHEMBL8704110 | 0.86 | KDM4E (0.55) | ILKKDM4ETNFNOD1RAB9A | |
| SCHEMBL4804958 | 0.85 | MAPT (0.56) | ILKKDM4ETNFNOD1RAB9A | |
| SCHEMBL3055139 | 0.85 | MAPT (0.69) | ILKKDM4ERAB9ANFKB1NFKB2 | |
| SCHEMBL12755312 | 0.84 | TNF (0.68) | KDM4ETNFNOD1RAB9ANFKB1 | |
| SCHEMBL12470428 | 0.84 | NR4A2 (0.46) | ILKKDM4ETNFNOD1RAB9A | |
| SCHEMBL12470685 | 0.83 | FFAR1 (0.52) | ILKKDM4ERAB9ANFKB1NFKB2 | |
| SCHEMBL12470914 | 0.82 | ILK (0.52) | ILKKDM4ERAB9ANFKB1NFKB2 | |
| SCHEMBL12470870 | 0.81 | KDM4E (0.59) | ILKKDM4ERAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491989-A | Iridium complex, preparation method of iridium complex, method for catalyzing and reducing water by using visible light and dye-sensitized solar cell | NANJING UNIVERSITY OF TECHNOLOGY | 2012-06-13 | — | — | CN | claimed |
| CN-103992291-B | Method for synthesizing 2-substituted benzothiazole derivative | NANJING TECH UNIVERSITY (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-103992291-A | Method for synthesizing 2-substituted benzothiazole derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2014-08-20 | — | — | CN | disclosed |
| US-8242278-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| CN-102491989-A | Iridium complex, preparation method of iridium complex, method for catalyzing and reducing water by using visible light and dye-sensitized solar cell | NANJING UNIVERSITY OF TECHNOLOGY | 2012-06-13 | — | — | CN | disclosed |
| CN-102491989-A | Iridium complex, preparation method of iridium complex, method for catalyzing and reducing water by using visible light and dye-sensitized solar cell | NANJING UNIVERSITY OF TECHNOLOGY | 2012-06-13 | — | — | CN | disclosed |
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI (JP) | 2012-04-26 | — | — | US | disclosed |
| EP-1473286-B1 | PROCESS FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI | 2009-08-27 | — | — | US | disclosed |
| US-7554000-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20050096471-A1 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | ILK 4732/4885KDM4E 3428/4885TNF 3672/4885 |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | ILK 4732/4885KDM4E 3428/4885TNF 3672/4885 |
| US-20050096471-A1 | Process for producing biaryl compound | PPOX, CAT, TYR | ILK 4732/4885KDM4E 3428/4885TNF 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.