SCHEMBL21386946

SCHEMBL21386946

Cc1ccnc(-c2cc(O)ccn2)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.74
CCR5 P51681 2/20 0.74
CCR8 P51685 2/20 0.74
METAP2 P50579 1/20 0.52
UHRF1 Q96T88 1/20 0.48
CYP2A6 P11509 1/20 0.47
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
KDM4E B2RXH2 1/20 0.45
NOS3 P29474 1/20 0.45
NOS1 P29475 1/20 0.45
NOS2 P35228 1/20 0.45
ACHE P22303 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
POLB P06746 1/20 0.42
PLAU P00749 1/20 0.41
ABL1 P00519 3/20 0.38
BCR P11274 3/20 0.38
GRM5 P41594 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9014049 1.00 CCR1 (0.74) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL9014388 1.00 CCR1 (0.74) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL9132287 0.98 CCR1 (0.71) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL9282369 0.98 CCR1 (0.71) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL9014363 0.86 CCR1 (0.65) CCR1CCR5CCR8METAP2CYP2A6
SCHEMBL181893 0.86 CCR1 (1.00) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL29397106 0.86 CCR1 (1.00) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL1071219 0.86 CCR1 (0.48) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL6820852 0.84 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL15664136 0.84 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110416586-B Iron-based flow battery, positive and negative electrolyte thereof and preparation method 江西理工大学 2020-09-11 CN disclosed
EP-2854948-B1 METAL-BASED THIOPHENE PHOTODYNAMIC COMPOUNDS AND THEIR USE MCFARLAND SHERRI ANN (CA) 2019-09-25 EP disclosed