Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.74 |
| ▸ | CCR5 | P51681 | 2/20 | 0.74 |
| ▸ | CCR8 | P51685 | 2/20 | 0.74 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | BCR | P11274 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014049 | 1.00 | CCR1 (0.74) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL21386946 | 1.00 | CCR1 (0.74) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL9132287 | 0.98 | CCR1 (0.71) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL9282369 | 0.98 | CCR1 (0.71) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL9014363 | 0.86 | CCR1 (0.65) | CCR1CCR5CCR8METAP2CYP2A6 | |
| SCHEMBL181893 | 0.86 | CCR1 (1.00) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL29397106 | 0.86 | CCR1 (1.00) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL1071219 | 0.86 | CCR1 (0.48) | CCR1CCR5CCR8MEN1KMT2A | |
| SCHEMBL6820852 | 0.84 | CCR1 (0.94) | CCR1CCR5CCR8METAP2UHRF1 | |
| SCHEMBL15664136 | 0.84 | CCR1 (0.94) | CCR1CCR5CCR8METAP2UHRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526603-B1 | Use of Mono, Bis or Tris (2,2'-substituted Bipyridine) complexes of a transition metal as mediators for current sensors | ASULAB SA (CH) | 1996-12-04 | — | — | EP | claimed |