Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309410 | 0.91 | CES2 (0.44) | MAPTMEN1KMT2ACES2CES1 | |
| SCHEMBL2797936 | 0.90 | CES2 (0.44) | MAPTMEN1KMT2AALDH1A1CES2 | |
| SCHEMBL21387055 | 0.89 | CES2 (0.53) | MAPTMEN1KMT2AALDH1A1CES2 | |
| SCHEMBL8160796 | 0.87 | CES2 (0.48) | MAPTMEN1KMT2ACES2CES1 | |
| SCHEMBL15956511 | 0.85 | CES2 (0.47) | MAPTMEN1KMT2ACES2CES1 | |
| SCHEMBL4313438 | 0.85 | CES2 (0.40) | HDAC1HDAC6MAPTMEN1KMT2A | |
| SCHEMBL4312458 | 0.84 | REN (0.45) | MAPTMEN1KMT2AALDH1A1CES2 | |
| SCHEMBL4316039 | 0.84 | CES2 (0.58) | MAPTCES2CES1HTTRAB9A | |
| SCHEMBL4322471 | 0.83 | TSHR (0.42) | MAPTALDH1A1CES2CES1HTT | |
| SCHEMBL15956962 | 0.83 | CES2 (0.56) | HDAC1HDAC6MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2956443-B1 | HYDANTOINS THAT MODULATE BACE-MEDIATED APP PROCESSING | BUCK INST RES AGING (US) | 2019-09-25 | — | — | EP | disclosed |