Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468392 | 0.83 | OPRM1 (0.81) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| Hydrocodone SCHEMBL2987 | 0.81 | OPRD1 (1.00) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| Hydrocodone SCHEMBL101731 | 0.81 | OPRD1 (1.00) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| Hydrocodone SCHEMBL12638883 | 0.81 | OPRD1 (1.00) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| Hydrocodone SCHEMBL277572 | 0.81 | OPRD1 (1.00) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| Hydrocodone SCHEMBL12402839 | 0.81 | OPRD1 (1.00) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| Hydrocodone SCHEMBL6744988 | 0.81 | OPRD1 (1.00) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| Hydrocodone SCHEMBL21335350 | 0.81 | OPRD1 (1.00) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| Hydrocodone SCHEMBL12013631 | 0.81 | OPRD1 (1.00) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| Hydrocodone SCHEMBL17523150 | 0.81 | OPRD1 (1.00) | OPRM1OPRD1OPRK1LMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3560336-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2019-10-30 | — | — | EP | disclosed |
| EP-2448407-B1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | KEMPHARM INC (US) | 2019-09-25 | — | — | EP | disclosed |