Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 4/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274382 | 1.00 | ZDHHC20 (0.45) | ZDHHC20ZDHHC2FAAHALDH1A1TSHR | |
| SCHEMBL8942370 | 0.98 | ZDHHC20 (0.43) | ZDHHC20ZDHHC2FAAHALDH1A1TSHR | |
| SCHEMBL24063928 | 0.93 | CA12 (0.41) | ZDHHC20ZDHHC2FAAHALDH1A1TSHR | |
| SCHEMBL20287509 | 0.87 | ALDH1A1 (0.39) | ZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL20274377 | 0.87 | ALDH1A1 (0.39) | ZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL375827 | 0.86 | TSHR (0.46) | ZDHHC20ZDHHC2TSHRCA12CA1 | |
| SCHEMBL4085872 | 0.86 | TSHR (0.46) | ZDHHC20ZDHHC2TSHRCA12CA1 | |
| SCHEMBL431375 | 0.86 | TSHR (0.46) | ZDHHC20ZDHHC2TSHRCA12CA1 | |
| SCHEMBL375647 | 0.86 | TSHR (0.46) | ZDHHC20ZDHHC2TSHRCA12CA1 | |
| SCHEMBL372624 | 0.86 | TSHR (0.46) | ZDHHC20ZDHHC2TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3542779-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2019-09-25 | — | — | EP | disclosed |