Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23613437 | 0.83 | ALDH1A1 (1.00) | ALDH1A1HSP90AA1MAPTNPSR1MEN1 | |
| SCHEMBL6680904 | 0.79 | APP (0.48) | ALDH1A1HSP90AA1MAPTNPSR1MEN1 | |
| SCHEMBL8837164 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HSP90AA1MAPTNPSR1MEN1 | |
| SCHEMBL7803648 | 0.77 | CASP3 (0.66) | ALDH1A1HSP90AA1MAPTNPSR1MEN1 | |
| SCHEMBL28634788 | 0.76 | ALDH1A1 (0.88) | ALDH1A1HSP90AA1MAPTNPSR1MEN1 | |
| SCHEMBL10887019 | 0.74 | CES1 (0.69) | ALDH1A1HSP90AA1MAPTNPSR1MEN1 | |
| SCHEMBL9555263 | 0.74 | CES1 (0.55) | ALDH1A1HSP90AA1MAPTNPSR1MEN1 | |
| SCHEMBL29410421 | 0.73 | CES1 (0.53) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL1982414 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HSP90AA1MAPTNPSR1MEN1 | |
| SCHEMBL28674642 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HSP90AA1MAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3542824-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | Tokyo University of Science Foundation (JP) | 2019-09-25 | — | — | EP | disclosed |