Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL4814063 | 0.98 | HPGD (0.49) | TDP1HPGDGPR35MEN1KMT2A | |
| SCHEMBL65199 | 0.84 | TDP1 (0.61) | TDP1GPR35MEN1KMT2AALDH1A1 | |
| SCHEMBL28927334 | 0.83 | MEN1 (0.48) | TDP1HPGDGPR35MEN1KMT2A | |
| 2-Nitroaniline SCHEMBL9847444 | 0.83 | PDE7A (0.51) | TDP1HPGDGPR35MEN1KMT2A | |
| SCHEMBL10778725 | 0.81 | HPGD (0.42) | TDP1HPGDMEN1KMT2ATTR | |
| SCHEMBL11722245 | 0.80 | TDP1 (0.62) | TDP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL58157 | 0.78 | TDP1 (0.65) | TDP1HPGDGPR35MEN1KMT2A | |
| SCHEMBL24548 | 0.78 | TDP1 (0.60) | TDP1GPR35MEN1KMT2AALDH1A1 | |
| SCHEMBL29460277 | 0.78 | TDP1 (0.65) | TDP1HPGDGPR35MEN1KMT2A | |
| SCHEMBL29448254 | 0.78 | TDP1 (0.60) | TDP1GPR35MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105621587-A | Method for degrading chloro-nitroaromatic by using sulfate radicals | UNIV ZHEJIANG | 2016-06-01 | — | — | CN | claimed |
| EP-0173202-B1 | PROCESS FOR THE PREPARATION OF CHLORO-O-NITROANILINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-28 | — | — | EP | claimed |
| EP-0173202-A2 | Process for the preparation of chloro-o-nitroanilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-05 | — | — | EP | claimed |
| EP-0007482-B1 | 2-CHLORO-6-NITROANILINES, PROCESS FOR THEIR PREPARATION, THEIR USE, HERBICIDAL COMPOSITIONS | CELAMERCK GmbH & Co. KG (DE) | 1981-09-16 | — | — | EP | claimed |
| EP-0007482-A1 | 2-Chloro-6-nitroanilines, process for their preparation, their use, herbicidal compositions | CELAMERCK GmbH & Co. KG (DE) | 1980-02-06 | — | — | EP | claimed |
| US-20260124214-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2026-05-07 | — | — | US | disclosed |
| EP-4419525-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LTD (GB) | 2025-07-23 | — | — | EP | disclosed |
| US-20250230165-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2025-07-17 | — | — | US | disclosed |
| US-20250163038-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. | 2025-05-22 | — | — | US | disclosed |
| US-20250101052-A1 | COMPOUND FOR EGFR KINASE INHIBITOR, COMPOSITION, AND USE THEREOF | INNOVATION INSTITUTE FOR ARTIFICIAL INTELLIGENCE IN MEDICINE OF ZHEJIANG UNIVERSITY (CN) | 2025-03-27 | — | — | US | disclosed |
| CN-116063283-B | 3-Amino indazole compound and application thereof | 暨南大学 | 2025-03-25 | — | — | CN | disclosed |
| US-20240425511-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2024-12-26 | — | — | US | disclosed |
| US-4172098-A | REACTION OF A HALOAMINOBENZOIC ACID WITH AN ALCOHOL AND NITROSYLATING AGENT IN THE PRESCENCE OF AN ACID AND WATER | BASF AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |
| US-4134978-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |
| US-4105655-A | PHENYL-AZO-ANILINO DYESTUFF | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-08 | — | — | US | disclosed |
| US-4083844-A | Phenylazo orthocyano phenylazo or orthocyano phenylazo phenylazo containing dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-4053527-A | REACTING HALONITROANILINES WITH ALCOHOLS AND NITROSATING AGENTS ION | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |
| US-4014647-A | DISPERSE DYES CONTAINING SULFONAMIDE GROUPS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |
| US-3978038-A | POLYAMIDES, POLYESTERS, POLYURETHANES | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
| US-3962209-A | PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124214-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | CBR1, NR3C1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TDP1 1135/4885HPGD 1203/4885GPR35 2263/4885 |
| US-20250163038-A1 | CBL-B MODULATORS AND USES THEREOF | CBLB, CBL, CBLC | TDP1 749/4885HPGD 4374/4885GPR35 4051/4885 |
| US-20250101052-A1 | COMPOUND FOR EGFR KINASE INHIBITOR, COMPOSITION, AND USE THEREOF | EGFR, ERBB2, ERBB3 | TDP1 4147/4885HPGD 4344/4885GPR35 1915/4885 |
| US-20250230165-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | NQO1, VHL, SDHA | TDP1 775/4885HPGD 18/4885GPR35 2529/4885 |
| US-20240425511-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | NQO1, VHL, SDHA | TDP1 775/4885HPGD 18/4885GPR35 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.