Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24795886 | 0.97 | ALDH1A1 (0.39) | ALDH1A1USP2MITFKLF5RAB9A | |
| SCHEMBL21389183 | 0.97 | ALDH1A1 (0.39) | ALDH1A1USP2MITFKLF5RAB9A | |
| SCHEMBL21389394 | 0.94 | GAA (0.38) | ALDH1A1USP2MITFKLF5RAB9A | |
| SCHEMBL26752482 | 0.89 | GAA (0.38) | ALDH1A1USP2MITFKLF5FABP3 | |
| SCHEMBL26744109 | 0.89 | GAA (0.38) | ALDH1A1USP2MITFKLF5FABP3 | |
| SCHEMBL26746350 | 0.88 | RAB9A (0.41) | ALDH1A1RAB9ASMN1; SMN2ATML3MBTL1 | |
| SCHEMBL24796295 | 0.86 | ATM (0.49) | ALDH1A1RAB9ASMN1; SMN2ATML3MBTL1 | |
| SCHEMBL21389343 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MITFRAB9ASMN1; SMN2ATM | |
| SCHEMBL26746271 | 0.85 | RAB9A (0.39) | ALDH1A1RAB9ASMN1; SMN2ATML3MBTL1 | |
| SCHEMBL24795943 | 0.84 | ALDH1A1 (0.39) | ALDH1A1RAB9ASMN1; SMN2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-11535660-B1 | Modulators of G-protein coupled receptors | Cannot Therapeutics, Inc. (US) | 2022-12-27 | — | — | US | disclosed |
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | ALDH1A1 3305/4885USP2 2595/4885MITF 1079/4885 |
| US-11535660-B1 | Modulators of G-protein coupled receptors | GIPR, GLP1R, GCGR | ALDH1A1 3367/4885USP2 2718/4885MITF 938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.