Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389478 | 0.96 | HTT (0.44) | HTTCYP1A2CYP3A4KMT2AALDH1A1 | |
| SCHEMBL24796137 | 0.86 | CYP1A2 (0.39) | HTTCYP1A2CYP3A4KMT2AALDH1A1 | |
| SCHEMBL24796003 | 0.86 | CYP1A2 (0.37) | HTTCYP1A2CYP3A4KMT2AALDH1A1 | |
| SCHEMBL24796298 | 0.85 | CYP1A2 (0.38) | HTTCYP1A2CYP3A4KMT2AALDH1A1 | |
| SCHEMBL21389419 | 0.85 | KMT2A (0.50) | KMT2AALDH1A1MEN1KDM4EPOLB | |
| SCHEMBL21389314 | 0.85 | CYP1A2 (0.37) | HTTCYP1A2CYP3A4KMT2AALDH1A1 | |
| SCHEMBL24795943 | 0.85 | ALDH1A1 (0.39) | CYP1A2CYP3A4KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24795907 | 0.85 | HPGD (0.43) | HTTKMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL21389187 | 0.84 | KMT2A (0.46) | CYP1A2CYP3A4KMT2AALDH1A1MEN1 | |
| SCHEMBL24796162 | 0.84 | CYP1A2 (0.42) | CYP1A2CYP3A4KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535660-B1 | Modulators of G-protein coupled receptors | Cannot Therapeutics, Inc. (US) | 2022-12-27 | — | — | US | disclosed |
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535660-B1 | Modulators of G-protein coupled receptors | GIPR, GLP1R, GCGR | HTT 689/4885CYP1A2 4309/4885CYP3A4 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.