Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24796162 | 0.86 | CYP1A2 (0.42) | CYP1A2CYP3A4ALDH1A1KMT2ARAB9A | |
| SCHEMBL21389478 | 0.86 | HTT (0.44) | CYP1A2CYP3A4ALDH1A1KMT2ARAB9A | |
| SCHEMBL21389166 | 0.85 | HTT (0.41) | CYP1A2CYP3A4ALDH1A1KMT2ARAB9A | |
| SCHEMBL24795943 | 0.85 | ALDH1A1 (0.39) | CYP1A2CYP3A4ALDH1A1KMT2ARAB9A | |
| SCHEMBL21389343 | 0.84 | ALDH1A1 (0.41) | CYP1A2CYP3A4ALDH1A1KMT2ARAB9A | |
| SCHEMBL21389313 | 0.83 | LMNA (0.47) | ALDH1A1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL21389154 | 0.83 | GAA (0.40) | ALDH1A1RAB9ANPC1HPGDKDM4E | |
| SCHEMBL24796302 | 0.83 | HPGD (0.44) | ALDH1A1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL26746416 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL24796300 | 0.81 | CYP1A2 (0.40) | CYP1A2CYP3A4ALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |