Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PER2 | O15055 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384206 | 0.76 | ALDH1A1 (0.52) | KDM4EPOLBHPGDLMNAALDH1A1 | |
| SCHEMBL18672535 | 0.74 | L3MBTL1 (0.67) | L3MBTL1KDM4EPOLBHPGDLMNA | |
| SCHEMBL20924684 | 0.73 | L3MBTL1 (0.62) | L3MBTL1KDM4EPOLBHPGDLMNA | |
| SCHEMBL9188836 | 0.72 | L3MBTL1 (0.61) | L3MBTL1KDM4EPOLBHPGDLMNA | |
| SCHEMBL9635362 | 0.72 | L3MBTL1 (0.61) | L3MBTL1KDM4EPOLBHPGDLMNA | |
| SCHEMBL9184161 | 0.72 | L3MBTL1 (0.61) | L3MBTL1KDM4EPOLBHPGDLMNA | |
| SCHEMBL6231346 | 0.72 | KDM4E (0.61) | L3MBTL1KDM4EPOLBHPGDLMNA | |
| SCHEMBL4464212 | 0.72 | KDM4E (0.61) | L3MBTL1KDM4EPOLBHPGDLMNA | |
| SCHEMBL12939885 | 0.72 | KDM4E (0.61) | L3MBTL1KDM4EPOLBHPGDLMNA | |
| SCHEMBL23585046 | 0.71 | L3MBTL1 (0.59) | L3MBTL1KDM4EPOLBHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |