Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2017491 | 0.90 | SMYD3 (0.55) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL19334411 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL27441717 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL10587847 | 0.81 | ALDH1A1 (0.83) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL27440891 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL24322791 | 0.79 | LMNA (0.58) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL2752779 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL2022247 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL2018034 | 0.78 | LMNA (0.61) | SMN1; SMN2ALDH1A1HPGDNPSR1EPHX1 | |
| SCHEMBL11804456 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |