Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389312 | 1.00 | ALDH1A1 (0.34) | ALDH1A1HSD17B10KDM4ETSHRFKBP1A | |
| SCHEMBL21389230 | 0.90 | USP2 (0.37) | ALDH1A1HSD17B10KDM4ETSHRKMT2A | |
| SCHEMBL24795884 | 0.90 | USP2 (0.37) | ALDH1A1HSD17B10KDM4ETSHRKMT2A | |
| SCHEMBL26746258 | 0.90 | KDM4E (0.33) | ALDH1A1HSD17B10KDM4ETSHRKMT2A | |
| SCHEMBL26746253 | 0.90 | KDM4E (0.33) | ALDH1A1HSD17B10KDM4ETSHRKMT2A | |
| SCHEMBL24796659 | 0.86 | L3MBTL1 (0.40) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL24796403 | 0.86 | L3MBTL1 (0.40) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL21389308 | 0.85 | CYP2C19 (0.38) | ALDH1A1HSD17B10TSHRSMN1; SMN2TP53 | |
| SCHEMBL26747755 | 0.85 | KDM4E (0.32) | ALDH1A1HSD17B10KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL24796402 | 0.84 | CYP1A2 (0.38) | ALDH1A1KDM4ESMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |